Advertisement

Perioperative Considerations for the Patient with Opioid Use Disorder on Buprenorphine, Methadone, or Naltrexone Maintenance Therapy

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribers receive full online access to your subscription and archive of back issues up to and including 2002.

      Content published before 2002 is available via pay-per-view purchase only.

      Subscribe:

      Subscribe to Anesthesiology Clinics
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

      1. Hedegaard H, Warner M, Minino AM. Drug overdose deaths in the United States, 1999-2016. In: NCHS Data Brief No.294, 2017. Available at: https://www.cdc.gov/nchs/products/databriefs/db294.htm. Accessed January 8, 2018.

        • Center for Behavioral Health Statistics and Quality
        2016 national survey on drug use and health: detailed tables.
        Substance Abuse and Mental Health Services Administration, Rockville (MD)2017
        • Sordo L.
        • Barrio G.
        • Bravo M.J.
        • et al.
        Mortality risk during and after opioid substitution treatment: systematic review and meta-analysis of cohort studies.
        BMJ. 2017; 357: j1550
        • Nielsen S.
        • Larance B.
        • Degenhardt L.
        • et al.
        Opioid agonist treatment for pharmaceutical opioid dependent people.
        Cochrane Database Syst Rev. 2016; (CD011117)
        • Mattick R.P.
        • Breen C.
        • Kimber J.
        • et al.
        Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence.
        Cochrane Database Syst Rev. 2014; (CD002207)
        • Amato L.
        • Davoli M.
        • Minozzi S.
        • et al.
        Methadone at tapered doses for the management of opioid withdrawal.
        Cochrane Database Syst Rev. 2013; (CD003409)
        • Dunn K.E.
        • Sigmon S.C.
        • Strain E.C.
        • et al.
        The association between outpatient buprenorphine detoxification duration and clinical treatment outcomes: a review.
        Drug Alcohol Depend. 2011; 119: 1-9
        • Strang J.
        • Babor T.
        • Caulkins J.
        • et al.
        Drug policy and the public good: evidence for effective interventions.
        Lancet. 2012; 379: 71-83
        • Lobmaier P.
        • Kornor H.
        • Kunoe N.
        • et al.
        Sustained-release naltrexone for opioid dependence.
        Cochrane Database Syst Rev. 2008; (CD006140)
        • Tanum L.
        • Solli K.
        • Latif Z.
        • et al.
        The effectiveness of injectable extended-release naltrexone vs daily buprenorphine-naloxone for opioid dependence: a randomized clinical noninferiority trial.
        JAMA Psychiatry. 2017; 74: 1197-1205
        • Lee J.D.
        • Nunes Jr., E.V.
        • Novo P.
        • et al.
        Comparative effectiveness of extended-release naltrexone versus buprenorphine-naloxone for opioid relapse prevention (X: BOT): a multicentre, open-label, randomized controlled trial.
        Lancet. 2018; 391: 309-318
        • Johnson R.E.
        • Fudala P.J.
        • Payne R.
        Buprenorphine: considerations for pain management.
        J Pain Symptom Manage. 2005; 29: 297-326
        • Center for Drug Evaluation and Research (U.S.)
        Orange book: approved drug products with therapeutic equivalence evaluations.
        37th edition. U.S. Dept. of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research, Office of Pharmaceutical Science, Office of Generic Drugs, Rockville (MD)2017
        • Raffa R.B.
        • Haidery M.
        • Huang H.M.
        • et al.
        The clinical analgesic efficacy of buprenorphine.
        J Clin Pharm Ther. 2014; 39: 577-583
        • Davis M.P.
        Twelve reasons for considering buprenorphine as a frontline analgesic in the management of pain.
        J Support Oncol. 2012; 10: 209-219
        • Dahan A.
        New insights into buprenorphine’s respiratory effects.
        in: Budd K. Raffa R.B. Buprenorphine- the unique opioid analgesic. Thieme, New York2005: 22-32
        • Walsh S.L.
        • Middleton L.S.
        Buprenorphine pharmacodynamics and pharmacokinetics.
        in: Cruciani R.A. Knotkova H. Handbook of methadone prescribing and buprenorphine therapy. Springer, New York2013: 163-181
        • Atkinson R.E.
        • Schofield P.
        • Mellor P.
        The efficacy in sequential use of buprenorphine and morphine in advanced cancer pain.
        in: Opioids in the treatment of cancer pain: proceedings of a symposium sponsored by Reckitt & Colman Pharmaceuticals and held at the Royal College of Surgeons, London. International congress and symposium series. 146. Royal Society of Medicine Services Limited, London1990: 81-87
        • Mercadante S.
        • Villari P.
        • Ferrera P.
        • et al.
        Safety and effectiveness of intravenous morphine for episodic breakthrough pain in patients receiving transdermal buprenorphine.
        J Pain Symptom Manage. 2006; 32: 175-179
        • Van Niel J.C.G.
        • Schneider J.
        • Tzschentke T.M.
        Efficacy of full μ-opioid receptor agonists is not impaired by concomitant buprenorphine or mixed opioid agonists/antagonists–preclinical and clinical evidence.
        Drug Res (Stuttg). 2016; 66: 562-570
        • Center for Substance Abuse Treatment
        Clinical guidelines for the use of buprenorphine in the treatment of opioid addiction. Treatment Improvement Protocol (TIP) Series 40. DHHS Publication No. (SMA) 04–3939.
        Substance Abuse and Mental Health Services Administration, Rockville (MD)2004
        • Silvia M.J.
        • Rubinstein A.
        Continuous perioperative sublingual buprenorphine.
        J Pain Palliat Care Pharmacother. 2016; 30: 289-293
        • Huang A.
        • Katznelson R.
        • de Perrot M.
        • et al.
        Perioperative management of a patient undergoing Clagett window closure stabilized on suboxone for chronic pain: a case report.
        Can J Anaesth. 2014; 61: 826-831
        • McCormick Z.
        • Chu S.K.
        • Chang-Chien G.C.
        • et al.
        Acute pain control challenges with buprenorphine/naloxone therapy in a patient with compartment syndrome secondary to McArdle’s disease: a case report and review.
        Pain Med. 2013; 14: 1187-1191
        • Kornfeld H.
        • Manfredi L.
        Effectiveness of full agonist opioids in patients stabilized on buprenorphine undergoing major surgery: a case series.
        Am J Ther. 2010; 17: 523-528
        • Roberts D.M.
        • Meyer-Witting M.
        High-dose buprenorphine: perioperative precautions and management strategies.
        Anaesth Intensive Care. 2005; 33: 17-25
        • Macintyre P.E.
        • Russell R.A.
        • Usher K.A.N.
        • et al.
        Pain relief and opioid requirements in the first 24 h after surgery in patients taking buprenorphine and methadone opioid substitution therapy.
        Anaesth Intensive Care. 2013; 41: 222-230
        • Meyer M.
        • Paranya G.
        • Norris A.K.
        • et al.
        Intrapartum and postpartum analgesia for women maintained on buprenorphine during pregnancy.
        Eur J Pain. 2010; 14: 939-943
        • Vilkins A.L.
        • Bagley S.M.
        • Hahn K.A.
        • et al.
        Comparison of post-cesarean section opioid analgesic requirements in women with opioid use disorder treated with methadone or buprenorphine.
        J Addict Med. 2017; 11: 397-401
        • Leighton B.L.
        • Crock L.W.
        Case series of successful postoperative pain management in buprenorphine maintenance therapy patients.
        Anesth Analg. 2017; 125: 1779-1783
        • Greenwald M.K.
        • Johanson C.E.
        • Moody D.E.
        • et al.
        Effects of buprenorphine maintenance dose on mu-opioid receptor availability, plasma concentrations, and antagonist blockade in heroin-dependent volunteers.
        Neuropsychopharmacology. 2003; 28: 2000-2009
        • Anderson T.A.
        • Quaye A.N.A.
        • Ward N.
        • et al.
        To stop or not, that is the question-acute pain management for the patient on chronic buprenorphine.
        Anesth Analg. 2017; 126: 1180-1186
        • Childers J.W.
        • Arnold R.M.
        Treatment of pain in patients taking buprenorphine for opioid addiction #221.
        J Palliat Med. 2012; 15: 613-614
        • Hammig R.
        • Kemter A.
        • Strasser J.
        • et al.
        Use of microdose for induction of buprenorphine treatment with overlapping full opioid agonist use: the Bernese method.
        Subst Abuse Rehabil. 2016; 7: 99-105
        • Kling M.A.
        • Carson R.E.
        • Borg L.
        • et al.
        Opioid receptor imaging with positron emission tomography and [(18)F]cyclofoxy in long-term, methadone-treated former heroin addicts.
        J Pharmacol Exp Ther. 2000; 295: 1070-1076
        • McCance-Katz E.F.
        • Sullivan L.E.
        • Nallani S.
        Drug interactions of clinical importance among the opioids, methadone and buprenorphine, and other frequently prescribed medications: a review.
        Am J Addict. 2010; 19: 4-16
        • Martin J.A.
        • Campbell A.
        • Killip T.
        • et al.
        QT interval screening in methadone maintenance treatment: report of a SAMHSA expert panel.
        J Addict Dis. 2011; 30: 283-306
        • Peng P.W.H.
        • Tumber P.S.
        • Gourlay D.
        Perioperative pain management of patients on methadone therapy.
        Can J Anaesth. 2005; 52: 513
      2. Methadone maintenance treatment program standards and clinical guidelines. 2011. Available at: http://www.cpso.on.ca/uploadedFiles/members/MMT-Guidelines.pdf. Accessed December 18, 2017.

        • Wentland M.P.
        • Lou R.
        • Lu Q.
        • et al.
        Syntheses of novel high affinity ligands for opioid receptors.
        Bioorg Med Chem Lett. 2009; 19: 2289-2294
        • Wall M.E.
        • Brine D.R.
        • Perez-Reyes M.
        The metabolismof naltrexone in man.
        NIDA Res Monogr. 1981; 28: 105-131
        • Sudakin D.
        Naltrexone: not just for opioids anymore.
        J Med Toxicol. 2016; 12: 71-75
        • Dunbar J.L.
        • Turncliff R.Z.
        • Dong Q.
        • et al.
        Single- and multiple-dose pharmacokinetics of long acting injectable naltrexone.
        Alcohol Clin Exp Res. 2006; 30: 480-490
        • Curatolo C.
        • Trinh M.
        Challenges in the perioperative management of the patient receiving extended-release naltrexone.
        A A Case Rep. 2014; 3: 142-144
        • Dean R.L.
        • Todtenkopf M.S.
        • Deaver D.R.
        • et al.
        Overriding the blockade of antinociceptive actions of opioids in rats treated with extended-release naltrexone.
        Pharmacol Biochem Behav. 2008; 89: 515-522
        • Díaz A.
        • Pazos A.
        • Flórez J.
        • et al.
        Regulation of mu-opioid receptors, G-protein-coupled receptor kinases and beta-arrestin 2 in the rat brain after chronic opioid receptor antagonism.
        Neuroscience. 2002; 112: 345-353
        • Tempel A.
        • Gardner E.L.
        • Zukin R.S.
        Neurochemical and functional correlates of naltrexone-induced opiate receptor up-regulation.
        J Pharmacol Exp Ther. 1985; 232: 439-444
        • Sigmon S.C.
        • Bisaga A.
        • Nunes E.V.
        • et al.
        Opioid detoxification and naltrexone induction strategies: recommendations for clinical practice.
        Am J Drug Alcohol Abuse. 2012; 38: 187-199
        • Huxtable C.A.
        • Roberts L.J.
        • Somogyi A.A.
        • et al.
        Acute pain management in opioid-tolerant patients: a growing challenge.
        Anaesth Intensive Care. 2011; 39: 804-823
        • Shah S.
        • Kapoor S.
        • Durkin B.
        Analgesic management of acute pain in the opioid-tolerant patient.
        Curr Opin Anaesthesiol. 2015; 28: 398-402
        • Kumar K.
        • Kirksey M.A.
        • Duong S.
        • et al.
        A review of opioid-sparing modalities in perioperative pain management: methods to decrease opioid use postoperatively.
        Anesth Analg. 2017; 125: 1749-1760
        • Richman J.M.
        • Liu S.S.
        • Courpas G.
        • et al.
        Does continuous peripheral nerve block provide superior pain control to opioids? A meta-analysis.
        Anesth Analg. 2006; 102: 248-257
        • Liu S.S.
        • Strodtbeck W.M.
        • Richman J.M.
        • et al.
        A comparison of regional versus general anesthesia for ambulatory anesthesia: a meta-analysis of randomized controlled trials.
        Anesth Analg. 2005; 101: 1634-1642
        • Meylan N.
        • Elia N.
        • Lysakowski C.
        • et al.
        Benefit and risk of intrathecal morphine without local anaesthetic in patients undergoing major surgery: meta-analysis of randomized trials.
        Br J Anaesth. 2009; 102: 156-167
        • Block B.M.
        • Liu S.S.
        • Rowlingson A.J.
        • et al.
        Efficacy of postoperative epidural analgesia: a meta-analysis.
        JAMA. 2003; 290: 2455-2463
        • Baeriswyl M.
        • Kirkham K.R.
        • Kern C.
        • et al.
        The analgesic efficacy of ultrasound-guided transversus abdominis plane block in adult patients: a meta-analysis.
        Anesth Analg. 2015; 121: 1640-1654
        • McEvoy M.
        • Scott M.J.
        • Gordon D.B.
        • et al.
        American Society for Enhanced Recovery (ASER) and Perioperative Quality Initiative (POQI) joint consensus statement on optimal analgesia within an enhanced recovery pathway for colorectal surgery: part 1-from the preoperative period to PACU.
        Perioper Med (Lond). 2017; 6: 8
        • McEvoy M.
        • Scott M.J.
        • Gordon D.B.
        • et al.
        American Society for Enhanced Recovery (ASER) and Perioperative Quality Initiative (POQI) joint consensus statement on optimal analgesia within an enhanced recovery pathway for colorectal surgery: part 2-from PACU to the transition home.
        Perioper Med. 2017; 6: 7
        • Bingham A.E.
        • Fu R.
        • Horn J.L.
        • et al.
        Continuous peripheral nerve block compared with single-injection peripheral nerve block a systematic review and meta-analysis of randomized controlled trials.
        Reg Anesth Pain Med. 2012; 37: 583-594
        • De Oliveira G.S.
        • Benzon H.T.
        • White P.F.
        The role of nonopioid analgesic infusions in the management of postoperative pain.
        in: Hadzic A. Hadzic's textbook of regional anesthesia and acute pain management. 2nd edition. McGraw-Hill, New York2017: 1226-1237
        • Laskowski K.
        • Stirling A.
        • McKay W.P.
        • et al.
        A systematic review of intravenous ketamine for postoperative analgesia.
        Can J Anaesth. 2011; 58: 911-923
        • Loftus R.W.
        • Yeager M.P.
        • Clark J.A.
        • et al.
        Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
        Anesthesiology. 2010; 113: 639-646
        • Prekupec M.P.
        • Sussman R.S.
        • Sher Y.
        • et al.
        Relapse on ketamine followed by severe and prolonged withdrawal.
        J Nat Sci. 2017; 3: 1-4
        • Kranke P.
        • Jokinen J.
        • Pace N.L.
        • et al.
        Continuous intravenous perioperative lidocaine infusion for postoperative pain and recovery.
        Cochrane Database Syst Rev. 2015; (CD009642)
        • Eipe N.
        • Gupta S.
        • Penning J.
        Intravenous lidocaine for acute pain: an evidence-based clinical update.
        BJA Educ. 2016; 16: 292-298
        • Weibel S.
        • Jokinen J.
        • Pace N.L.
        • et al.
        Efficacy and safety of intravenous lidocaine for postoperative analgesia and recovery after surgery: a systematic review with trial sequential analysis.
        Br J Anaesth. 2016; 116: 770-783
        • Dunn L.K.
        • Durieux M.E.
        Perioperative use of intravenous lidocaine.
        Anesthesiology. 2017; 126: 729-737
        • De Oliveira Jr., G.S.
        • Castro-Alves L.J.
        • Khan J.H.
        • et al.
        Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
        Anesthesiology. 2013; 119: 178-190
        • Song J.W.
        • Lee Y.W.
        • Yoon K.B.
        • et al.
        Magnesium sulfate prevents remifentanil-induced postoperative hyperalgesia in patients undergoing thyroidectomy.
        Anesth Analg. 2011; 113: 390-397
        • Young A.C.
        • Buvanendran A.
        Multimodal analgesia: pharmacologic interventions and prevention of persistent postoperative pain.
        in: Hadzic A. Hadzic's textbook of regional anesthesia and acute pain management. 2nd edition. McGraw-Hill, New York2017: 1219-1226
        • McNicol E.D.
        • Ferguson M.C.
        • Haroutounian S.
        • et al.
        Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain.
        Cochrane Database Syst Rev. 2016; (CD007126)
        • Jibril F.
        • Sharaby S.
        • Mohamed A.
        • et al.
        Intravenous versus oral acetaminophen for pain: systematic review of current evidence to support clinical decision-making.
        Can J Hosp Pharm. 2015; 68: 238-247
        • Kaye A.D.
        • Cornett E.M.
        • Helander E.
        • et al.
        An update on nonopioids intravenous or oral analgesics for perioperative pain management.
        Anesthesiol Clin. 2017; 35: 55-71
        • Hurley R.W.
        • Cohen S.P.
        • Williams K.A.
        • et al.
        The analgesic effects of perioperative gabapentin on postoperative pain: a meta-analysis.
        Reg Anesth Pain Med. 2006; 31: 237-247
        • Arumugam S.
        • Lau C.S.M.
        • Chamberlain R.S.
        Use of preoperative gabapentin significantly reduces postoperative opioid consumption: a meta-analysis.
        J Pain Res. 2016; 9: 631-640
        • Moghadam M.S.
        • Alavinia M.
        The effects of gabapentin on methadone based addiction treatment: a randomized controlled trial.
        Pak J Pharm Sci. 2013; 26: 985-989
        • Sanders N.C.
        • Mancino M.J.
        • Gentry W.B.
        • et al.
        Randomized, placebo-controlled pilot trial of gabapentin during an outpatient, buprenorphine-assisted detoxification procedure.
        Exp Clin Psychopharmacol. 2013; 21: 294-302
        • Moore R.A.
        • Derry S.
        • Aldington D.
        • et al.
        Single dose oral analgesics for acute postoperative pain in adults - an overview of Cochrane reviews.
        Cochrane Database Syst Rev. 2015; (CD008659)
        • Alexander R.
        • El-Moalem H.E.
        • Gan T.J.
        Comparison of the morphine- sparing effects of diclofenac sodium and ketoroiac tromethamine after major orthopedic surgery.
        J Clin Anesth. 2002; 14: 187-192
        • Straube S.
        • Derry S.
        • McQuay H.J.
        • et al.
        Effect of preoperative Cox-II-selective NSAIDs (coxibs) on postoperative outcomes: a systematic review of randomized studies.
        Acta Anaesthesiol Scand. 2005; 49: 601-613
        • De Oliveira Jr., G.S.
        • Agarwal D.
        • Benzon H.T.
        Perioperative single dose ketorolac to prevent postoperative pain: a meta-analysis of randomized trials.
        Anesth Analg. 2012; 114: 424-433
        • De Oliveira Jr., G.S.
        • Almeida M.D.
        • Benzon H.T.
        • et al.
        Perioperative single dose systemic dexamethasone for postoperative pain: a meta-analysis of randomized controlled trials.
        Anesthesiology. 2011; 115: 575-588
        • Tang C.
        • Xia Z.
        Dexmedetomidine in perioperative acute pain management: a non-opioid adjuvant analgesic.
        J Pain Res. 2017; 11: 1899-1904
        • Blaudszun G.
        • Lysakowski C.
        • Elia N.
        • et al.
        Effect of perioperative systemic alpha2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials.
        Anesthesiology. 2012; 116: 1312-1322
        • Wenzel J.T.
        • Schwenk E.S.
        • Baratta J.L.
        • et al.
        Managing opioid-tolerant patients in the perioperative surgical home.
        Anesthesiol Clin. 2016; 34: 287-301
        • Gelineau A.M.
        • King M.R.
        • Ladha K.S.
        • et al.
        Intraoperative esmolol as an adjunct for perioperative opioid and postoperative pain reduction: a systematic review, meta-analysis, and meta-regression.
        Anesth Analg. 2018; 126: 1035-1049
        • Darnall B.D.
        Pain psychology and pain catastrophizing in the perioperative setting: a review of impacts, interventions and unmet needs.
        Hand Clin. 2016; 32: 33-39
        • Garland E.L.
        • Baker A.K.
        • Larsen P.
        • et al.
        Randomized controlled trial of brief mindfulness training and hypnotic suggestion for acute pain relief in the hospital setting.
        J Gen Intern Med. 2017; 32: 1106-1113