The Diagnostic Workup of Patients with Neuropathic Pain

Neuropathic pain is initiated or caused by damage or dysfunction of the peripheral or central nervous systems in various disorders, each having pain-related symptoms and signs thought secondary to common pain mechanisms. Ancillary testing may demonstrate associated nervous system abnormalities, however its specificity is inadequate at present, as it makes inferential conclusions from indirect data. Symptom assessment and physical findings remain paramount in the diagnosis of neuropathic pain.